Steve Carell

Gru (voice)

Pierre Coffin

Kevin / Stuart / Bob / Minions (voice)

Alan Arkin

Wild Knuckles (voice)

Taraji P. Henson

Belle Bottom (voice)

Julie Andrews

Gru's Mom (voice)

Jean-Claude Van Damme

Jean Clawed (voice)

Lucy Lawless

Nun-Chuck (voice)

Michelle Yeoh

Master Chow (voice)

Dolph Lundgren

Svengeance (voice)

Danny Trejo

Stronghold (voice)

Russell Brand

Dr. Nefario (voice)

Jimmy O. Yang

Henchman 1 (voice)

Kevin Michael Richardson

Henchman 2 (voice)

John DiMaggio

Henchman 3 (voice)

RZA

Biker (voice)

Michael Beattie

VNC Announcer / Guru Rick (voice)

Will Arnett

Mr. Perkins (voice)

Steve Coogan

Silas Ramsbottom (voice)

Colette Whitaker

Gru's Teacher (voice)

Raymond S. Persi

Birthday Kid (voice)